BDBM50156764 5-(9-oxo-9H-xanthen-2-yloxy)pentanoic acid::CHEMBL222502

SMILES OC(=O)CCCCOc1ccc2oc3ccccc3c(=O)c2c1

InChI Key InChIKey=ZCUWRMCUAYZEHP-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50156764   

TargetNAD-dependent protein deacetylase sirtuin-2(Human)
University of Kuopio

Curated by ChEMBL
LigandPNGBDBM50156764(5-(9-oxo-9H-xanthen-2-yloxy)pentanoic acid | CHEMB...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of human recombinant GST-tagged SIRT2 by histone deacetylase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLong-chain-fatty-acid--CoA ligase 6(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50156764(5-(9-oxo-9H-xanthen-2-yloxy)pentanoic acid | CHEMB...)
Affinity DataIC50: 9.30E+4nMAssay Description:Inhibition of recombinant human ACSL6 assessed as reduction in acetyl-coA prodution incubated for 60 mins in presence of Coenzyme A, ATP and MgCl2 by...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLong-chain-fatty-acid--CoA ligase 4(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50156764(5-(9-oxo-9H-xanthen-2-yloxy)pentanoic acid | CHEMB...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of recombinant human ACSL4 assessed as reduction in acetyl-coA prodution incubated for 120 mins in presence of Coenzyme A, ATP and MgCl2 b...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLong-chain-fatty-acid--CoA ligase 5(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50156764(5-(9-oxo-9H-xanthen-2-yloxy)pentanoic acid | CHEMB...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of recombinant human ACSL5 assessed as reduction in acetyl-coA prodution incubated for 90 mins in presence of Coenzyme A, ATP and MgCl2 by...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFatty acid CoA ligase Acsl3(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50156764(5-(9-oxo-9H-xanthen-2-yloxy)pentanoic acid | CHEMB...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of recombinant human ACSL3 assessed as reduction in acetyl-coA prodution incubated for 90 mins in presence of Coenzyme A, ATP and MgCl2 by...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLong-chain-fatty-acid--CoA ligase 1(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50156764(5-(9-oxo-9H-xanthen-2-yloxy)pentanoic acid | CHEMB...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of ACSL1 (unknown origin) assessed as reduction in acetyl-coA prodution incubated for 90 mins in presence of Coenzyme A, ATP and MgCl2 by ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed