BDBM50156628 (R)-2-furan-2-yl-7-(hexahydropyrrolo[1,2-a]pyrazin-2-yl)[1,2,4]triazolo[1,5-c]pyrimidin-5-ylamine::(S)-2-furan-2-yl-7-(hexahydro-pyrrolo[1,2-a]pyrazin-2-yl)-[1,2,4]triazolo[1,5-c]pyrimidin-5-ylamine::CHEMBL426738

SMILES Nc1nc(cc2nc(nn12)-c1ccco1)N1CCN2CCC[C@@H]2C1

InChI Key InChIKey=DBVSAWLRBJEGLH-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50156628   

TargetAdenosine receptor A2a(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50156628((S)-2-furan-2-yl-7-(hexahydro-pyrrolo[1,2-a]pyrazi...)
Affinity DataKi:  63nMAssay Description:Inhibition of rat recombinant adenosine receptor A2aMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A2a(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50156628((S)-2-furan-2-yl-7-(hexahydro-pyrrolo[1,2-a]pyrazi...)
Affinity DataKi:  63nMAssay Description:Displacement of [3H]ZM241385 from adenosine A2A receptor in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A2a(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50156628((S)-2-furan-2-yl-7-(hexahydro-pyrrolo[1,2-a]pyrazi...)
Affinity DataKi:  63nMAssay Description:Antagonist activity at human adenosine A2A receptorMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetAdenosine receptor A1(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50156628((S)-2-furan-2-yl-7-(hexahydro-pyrrolo[1,2-a]pyrazi...)
Affinity DataKi:  1.07E+3nMAssay Description:Inhibition of rat recombinant adenosine A1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A1(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50156628((S)-2-furan-2-yl-7-(hexahydro-pyrrolo[1,2-a]pyrazi...)
Affinity DataKi:  1.10E+3nMAssay Description:Displacement of [3h]DPCPX from adenosine A receptor in rat cerebral cortex membraneMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A1(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50156628((S)-2-furan-2-yl-7-(hexahydro-pyrrolo[1,2-a]pyrazi...)
Affinity DataKi:  1.10E+3nMAssay Description:Antagonist activity at human adenosine A1 receptorMore data for this Ligand-Target Pair
In DepthDetails
PubMed