BDBM50156311 CHEMBL187620::N-arylpiperazine derivative

SMILES COC(=O)C1C(C(C(=O)OC)=C(C)N=C1C)c1cccc(NC(NCCNC2CCN(CC2)c2ccccc2OC)=NC#N)c1

InChI Key InChIKey=UOTOARZOADGZAP-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50156311   

TargetNeuropeptide Y receptor type 1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50156311(N-arylpiperazine derivative | CHEMBL187620)
Affinity DataIC50: 4nMAssay Description:Inhibition of binding of [125I]PYY to membranes of SK-N-MC cells expressing the human Y1 receptorsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50156311(N-arylpiperazine derivative | CHEMBL187620)
Affinity DataKi:  3.60nMAssay Description:Antagonist activity towards Neuropeptide Y receptor type 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed