BDBM50156164 CHEMBL3780386

SMILES COCC(=O)N(C)c1cc(COc2ccc(NC(=O)Nc3cc(nn3-c3ccc(C)cc3)C(C)(C)C)c3ccccc23)ccn1

InChI Key InChIKey=AHJFDPDQMITANM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50156164   

TargetMitogen-activated protein kinase 12(Human)
Sygnature Discovery

Curated by ChEMBL
LigandPNGBDBM50156164(CHEMBL3780386)
Affinity DataIC50: 2.44E+3nMAssay Description:Inhibition of human recombinant p38 gamma assessed as phosphorylation of MAPKAP-K2 preincubated for 2 hrs followed by FRET peptide and MAPKAP-K2 addi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/12/2017
Entry Details Article
PubMed
TargetTyrosine-protein kinase HCK(Human)
Sygnature Discovery

Curated by ChEMBL
LigandPNGBDBM50156164(CHEMBL3780386)
Affinity DataIC50: 8.67E+3nMAssay Description:Inhibition of HCK (unknown origin) preincubated for 2 hrs followed by FRET peptide addition measured after 1 hr by Z-LYTE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/12/2017
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Sygnature Discovery

Curated by ChEMBL
LigandPNGBDBM50156164(CHEMBL3780386)
Affinity DataIC50: 27nMAssay Description:Inhibition of human recombinant p38 alpha assessed as phosphorylation of MAPKAP-K2 preincubated for 2 hrs followed by FRET peptide and MAPKAP-K2 addi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/12/2017
Entry Details Article
PubMed