BDBM50156163 CHEMBL3780832

SMILES Cc1ccc(cc1)-n1nc(cc1NC(=O)Nc1ccc(OCc2ccnc(NC(=O)CS(C)(=O)=O)c2)c2ccccc12)C(C)(C)C

InChI Key InChIKey=ITENSOATZCMKDD-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50156163   

TargetMitogen-activated protein kinase 12(Human)
Sygnature Discovery

Curated by ChEMBL
LigandPNGBDBM50156163(CHEMBL3780832)
Affinity DataIC50: 55nMAssay Description:Inhibition of human recombinant p38 gamma assessed as phosphorylation of MAPKAP-K2 preincubated for 2 hrs followed by FRET peptide and MAPKAP-K2 addi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/12/2017
Entry Details Article
PubMed
TargetTyrosine-protein kinase HCK(Human)
Sygnature Discovery

Curated by ChEMBL
LigandPNGBDBM50156163(CHEMBL3780832)
Affinity DataIC50: 110nMAssay Description:Inhibition of HCK (unknown origin) preincubated for 2 hrs followed by FRET peptide addition measured after 1 hr by Z-LYTE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/12/2017
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Sygnature Discovery

Curated by ChEMBL
LigandPNGBDBM50156163(CHEMBL3780832)
Affinity DataIC50: 8nMAssay Description:Inhibition of human recombinant p38 alpha assessed as phosphorylation of MAPKAP-K2 preincubated for 2 hrs followed by FRET peptide and MAPKAP-K2 addi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/12/2017
Entry Details Article
PubMed