BDBM50156024 CHEMBL3780852

SMILES CCCCCn1c2cc(F)ccc2c(O)c(C(=O)NC23CC4CC(CC(C4)C2)C3)c1=O

InChI Key InChIKey=QHSJVMXTEFKMQK-UHFFFAOYSA-N

Data  3 KI  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50156024   

TargetCannabinoid receptor 2(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50156024(CHEMBL3780852)
Affinity DataIC50: 3.5nMAssay Description:Displacement of [3H]-CP-55940 from human recombinant CB2 receptor expressed in HEK293 cells after 90 mins by Competition binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/12/2017
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50156024(CHEMBL3780852)
Affinity DataEC50:  18nMAssay Description:Inverse agonist activity at recombinant human CB2 receptor expressed in CHO-K1 cells assessed as increase in NHK477-induced cAMP production by lumine...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/12/2017
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50156024(CHEMBL3780852)
Affinity DataKi:  0.800nMAssay Description:Binding affinity towards human CB2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetCannabinoid receptor 2(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50156024(CHEMBL3780852)
Affinity DataKi:  0.930nMAssay Description:Displacement of [3H]-CP-55940 from human recombinant CB2 receptor expressed in HEK293 cells after 90 mins by Competition binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/12/2017
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50156024(CHEMBL3780852)
Affinity DataKi:  1.28E+3nMAssay Description:Displacement of [3H]-CP-55940 from human recombinant CB1 receptor expressed in HEK293 cells after 90 mins by Competition binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/12/2017
Entry Details Article
PubMed