BDBM50155923 CHEMBL3781583

SMILES CC(C)c1cc(Cl)cc(C(C)C)c1NC(=O)NS(=O)(=O)c1cccc(c1)C(C)(C)O

InChI Key InChIKey=YRSBLSHMKVQWHP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50155923   

TargetNACHT, LRR and PYD domains-containing protein 3(Human)
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50155923(CHEMBL3781583)
Affinity DataIC50: 260nMAssay Description:Reversible inhibition of NLRP3 in LPS activated human monocytes after 30 mins by ELISA analysis in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2017
Entry Details Article
PubMed