BDBM50155803 CHEMBL3793455::US9505736, (1S,2S,3S)-1-Chloro-N-hydroxy-2-(4-(5- methylpyrimidin-2-yl)phenyl)-3- phenylcyclopropanecarboxamide

SMILES Cc1cnc(nc1)-c1ccc(cc1)[C@@H]1[C@@H](c2ccccc2)[C@@]1(Cl)C(=O)NO

InChI Key InChIKey=ZOHXVMRBDNGIDM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50155803   

TargetHistone deacetylase 4 [648-729,745-1057](Human)
Chdi Foundation

US Patent
LigandPNGBDBM50155803(US9505736, (1S,2S,3S)-1-Chloro-N-hydroxy-2-(4-(5- ...)
Affinity DataIC50: 110nMpH: 8.0 T: 2°CAssay Description:The potency of Class IIa Histone Deacetylase (HDAC) inhibitors is quantified by measuring the Histone Deacetylase 4 (HDAC4) catalytic domain enzymati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2017
Entry Details
Go to US Patent

TargetHistone deacetylase 4(Human)
Biofocus

Curated by ChEMBL
LigandPNGBDBM50155803(US9505736, (1S,2S,3S)-1-Chloro-N-hydroxy-2-(4-(5- ...)
Affinity DataIC50: 1.15E+3nMAssay Description:Inhibition of HDAC4 in human Jurkat E6-1 cells using Lys-TFA as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2017
Entry Details Article
PubMed