BDBM50155749 CHEMBL3781625

SMILES COc1ccc(cc1)-n1ncc2c(ncnc12)N1CCN(CC1)c1ccccc1OC

InChI Key InChIKey=HXRCCVXGXJOFHE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50155749   

LigandPNGBDBM50155749(CHEMBL3781625)
Affinity DataIC50: 170nMAssay Description:Inhibition of human GLUT3 expressed in GLUT1 knock-out DLD1 cells assessed as ATP production co-incubated with 300 mM glucose for 16 hrs by CellTiter...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50155749(CHEMBL3781625)
Affinity DataIC50: 230nMAssay Description:Inhibition of human GLUT1 expressed in DLD1 cells assessed as ATP production co-incubated with 100 mM glucose for 16 hrs by CellTiter-Glo assay in pr...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50155749(CHEMBL3781625)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of human GLUT2 expressed in CHO cells assessed as ATP production co-incubated with 30 mM fructose for 16 hrs by CellTiter-Glo assay in pre...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed