BDBM50155151 4-((1-methyl-1H-indol-3-yl)methylene)-3-(pyrazin-2-yl)-1H-pyrazol-5(4H)-one::4-(1-Methyl-1H-indol-3-ylmethylene)-5-pyrazin-2-yl-2,4-dihydro-pyrazol-3-one::CHEMBL364411

SMILES Cn1cc(\C=C2/C(=O)NN=C2c2cnccn2)c2ccccc12

InChI Key InChIKey=IVBFAQHEEUITPW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50155151   

TargetVascular endothelial growth factor receptor 2(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50155151(4-(1-Methyl-1H-indol-3-ylmethylene)-5-pyrazin-2-yl...)
Affinity DataIC50: 230nMAssay Description:Inhibition of Vascular endothelial growth factor receptor 2(KDR) with DTT (dithiothreitol)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50155151(4-(1-Methyl-1H-indol-3-ylmethylene)-5-pyrazin-2-yl...)
Affinity DataIC50: 100nMAssay Description:Inhibition of Vascular endothelial growth factor receptor 2(KDR) without DTT (dithiothreitol)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50155151(4-(1-Methyl-1H-indol-3-ylmethylene)-5-pyrazin-2-yl...)
Affinity DataIC50: 37nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed