BDBM50154931 CHEMBL3775792

SMILES CC(C)c1n[nH]c2c(NCc3ccc(cc3)-c3ccccn3)nc(NCC(C)(C)O)nc12

InChI Key InChIKey=BSQNZDHZPYKQMW-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50154931   

TargetCyclin-dependent kinase 5(Human)
Palack£

Curated by ChEMBL
LigandPNGBDBM50154931(CHEMBL3775792)
Affinity DataIC50: 1nMAssay Description:Inhibition of CDK5 (unknown origin) using histone H1 as substrate in presence of [gamma33P]-ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2017
Entry Details Article
PubMed
LigandPNGBDBM50154931(CHEMBL3775792)
Affinity DataIC50: 9nMAssay Description:Inhibition of CDK2/Cyclin E (unknown origin) expressed in sf9 cells using histone H1 as substrate in presence of [gamma33P]-ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2017
Entry Details Article
PubMed
TargetCyclin-dependent kinase 5(Human)
Palack£

Curated by ChEMBL
LigandPNGBDBM50154931(CHEMBL3775792)
Affinity DataIC50: 1nMAssay Description:Inhibition of CDK5 (unknown origin) expressed in baculovirus infected Sf9 cells in presence of [gamma-33p]-ATP and ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetCyclin-dependent kinase 2(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50154931(CHEMBL3775792)
Affinity DataIC50: 9nMAssay Description:Inhibition of CDK2 (unknown origin) expressed in baculovirus infected Sf9 cells in presence of [gamma-33p]-ATP and ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed