BDBM50154705 4-Methoxy-N-{3-[4-(2-methoxy-phenyl)-piperazin-1-yl]-propyl}-benzenesulfonamide::4-Methoxy-N-{3-[4-(o-methoxyphenyl)-piperazin-1-yl]-propyl}-benzenesulfonamide::CHEMBL427518

SMILES COc1ccc(cc1)S(=O)(=O)NCCCN1CCN(CC1)c1ccccc1OC

InChI Key InChIKey=FJGYVPIKFQWJJI-UHFFFAOYSA-N

Data  3 KI  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50154705   

Target5-hydroxytryptamine receptor 7(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50154705(4-Methoxy-N-{3-[4-(o-methoxyphenyl)-piperazin-1-yl...)
Affinity DataIC50: 37nMAssay Description:Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50154705(4-Methoxy-N-{3-[4-(o-methoxyphenyl)-piperazin-1-yl...)
Affinity DataIC50: 272nMAssay Description:Displacement of [3H]8-OH-DPAT from human recombinant 5HT1A receptor expressed in CHOK1 cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50154705(4-Methoxy-N-{3-[4-(o-methoxyphenyl)-piperazin-1-yl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50154705(4-Methoxy-N-{3-[4-(o-methoxyphenyl)-piperazin-1-yl...)
Affinity DataIC50: 5.17E+3nMAssay Description:Displacement of [3H]ketanserin from human recombinant 5HT2A receptor expressed in CHOK1 cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50154705(4-Methoxy-N-{3-[4-(o-methoxyphenyl)-piperazin-1-yl...)
Affinity DataIC50: 9.67E+3nMAssay Description:Displacement of [3H]mesulergine from human recombinant 5HT2C receptor expressed in CHOK1 cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50154705(4-Methoxy-N-{3-[4-(o-methoxyphenyl)-piperazin-1-yl...)
Affinity DataKi:  37nMAssay Description:Antagonist activity at 5-HT7 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
State University of Groningen

Curated by ChEMBL
LigandPNGBDBM50154705(4-Methoxy-N-{3-[4-(o-methoxyphenyl)-piperazin-1-yl...)
Affinity DataKi:  100nMAssay Description:Binding affinity towards rat 5-HT7 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50154705(4-Methoxy-N-{3-[4-(o-methoxyphenyl)-piperazin-1-yl...)
Affinity DataKi:  272nMAssay Description:Antagonist activity at 5-HT1A receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed