BDBM50154422 (S)-2-[(R)-2-(4-Dimethylamino-phenyl)-1,3-dioxo-octahydro-pyrido[1,2-c]pyrimidin-5-ylamino]-3-(1H-indol-3-yl)-propionic acid adamantan-2-yl ester::CHEMBL364334

SMILES CN(C)c1ccc(cc1)N1C(=O)CC2[C@@H](CCCN2C1=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)OC1C2CC3CC(C2)CC1C3

InChI Key InChIKey=JFEMEKUOHMARQZ-UHFFFAOYSA-N

Data  4 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50154422   

TargetGastrin/cholecystokinin type B receptor(Human)
Instituto De Qu£Mica M£Dica (Csic)

Curated by ChEMBL
LigandPNGBDBM50154422((S)-2-[(R)-2-(4-Dimethylamino-phenyl)-1,3-dioxo-oc...)
Affinity DataIC50: 723nMAssay Description:Inhibition of 125I]-BH-(Thr,Nle)-CCK-9 binding to human CCK2 receptor expressed in COS-7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Human)
Instituto De Qu£Mica M£Dica (Csic)

Curated by ChEMBL
LigandPNGBDBM50154422((S)-2-[(R)-2-(4-Dimethylamino-phenyl)-1,3-dioxo-oc...)
Affinity DataEC50:  517nMAssay Description:Inhibition of (Thr,Nle)-CCK-9 -induced inositol phosphate production in COS-7 cells expressing human CCK2 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Human)
Instituto De Qu£Mica M£Dica (Csic)

Curated by ChEMBL
LigandPNGBDBM50154422((S)-2-[(R)-2-(4-Dimethylamino-phenyl)-1,3-dioxo-oc...)
Affinity DataIC50: 4.47E+3nMAssay Description:Inhibition of (Thr,Nle)-CCK-9-induced inositol phosphate production in COS-7 cells expressing human CCK2 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Rat)
Instituto De Qu£Mica M£Dica (Csic)

Curated by ChEMBL
LigandPNGBDBM50154422((S)-2-[(R)-2-(4-Dimethylamino-phenyl)-1,3-dioxo-oc...)
Affinity DataIC50: 276nMAssay Description:Inhibition of [3H]-pCCK-8 binding to Cholecystokinin type B receptor of rat cerebral cortex homogenatesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholecystokinin receptor type A(Rat)
Instituto De Qu£Mica M£Dica (Csic)

Curated by ChEMBL
LigandPNGBDBM50154422((S)-2-[(R)-2-(4-Dimethylamino-phenyl)-1,3-dioxo-oc...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [3H]-pCCK-8 binding to Cholecystokinin type A receptor of rat pancreas homogenatesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed