BDBM50153340 CHEMBL3775245

SMILES OC(=O)c1ccncc1NC(=O)CCc1ccccc1

InChI Key InChIKey=MPQSISPRVFNNSB-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50153340   

TargetLysine-specific demethylase 4D(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50153340(CHEMBL3775245)
Affinity DataIC50: 398nMAssay Description:Inhibition of human KDM4D (11 to 341 residues) using H3K9Me3 peptide as substrate assessed as demethylation of substrate by Rapidfire mass spectromet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2017
Entry Details Article
PubMed
TargetLysine-specific demethylase 4C(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50153340(CHEMBL3775245)
Affinity DataIC50: 316nMAssay Description:Inhibition of KDM4C (unknown origin) using H3K9Me3 peptide as substrate assessed as demethylation of substrate by Rapidfire mass spectrometric analys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2017
Entry Details Article
PubMed
TargetLysine-specific demethylase 6B(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50153340(CHEMBL3775245)
Affinity DataIC50: 3.98E+4nMAssay Description:Inhibition of human KDM6B catalytic domain using H3(20 to 36 residues)K27Me3 peptide as substrate assessed as demethylation of substrate by Rapidfire...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2017
Entry Details Article
PubMed
TargetProlyl hydroxylase EGLN3(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50153340(CHEMBL3775245)
Affinity DataIC50: 3.16E+4nMAssay Description:Inhibition of full length His-MBP-att-EGLN3 (1 to 239 residues) (unknown origin) in Escherichia coli BL21(DE3)pRR692 cells assessed as hydroxylation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2017
Entry Details Article
PubMed