BDBM50153175 6-[3-(4-Cyano-benzyl)-3H-imidazol-4-ylmethoxymethyl]-3''-methoxy-biphenyl-3-carbonitrile::CHEMBL187175

SMILES COc1cccc(c1)-c1cc(ccc1COCc1cncn1Cc1ccc(cc1)C#N)C#N

InChI Key InChIKey=NUJXPVZUWBELDZ-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50153175   

LigandPNGBDBM50153175(6-[3-(4-Cyano-benzyl)-3H-imidazol-4-ylmethoxymethy...)
Affinity DataEC50:  32nMAssay Description:Reduced farnesylation in H-Ras NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50153175(6-[3-(4-Cyano-benzyl)-3H-imidazol-4-ylmethoxymethy...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [3H]GGPP incorporation into C-terminus of K-Ras by human Geranylgeranyl transferase type IMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDimer of Protein farnesyltransferase subunit beta(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50153175(6-[3-(4-Cyano-benzyl)-3H-imidazol-4-ylmethoxymethy...)
Affinity DataIC50: 0.460nMAssay Description:Inhibition of [3H]FPP incorporation into recombinant Ras CVIM by human FarnesyltransferaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed