BDBM50153093 CHEMBL3775668

SMILES O=c1[nH]cnc2c(nccc12)-n1cc(CCN2CCC(CC2)c2cccs2)cn1

InChI Key InChIKey=XIVQRYFYMNIDET-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50153093   

TargetLysine-specific demethylase 3A(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50153093(CHEMBL3775668)
Affinity DataIC50: 8.30E+3nMAssay Description:Inhibition of KDM3A (unknown origin) using biotin-H3K9me2 (1 to 21 residues) as substrate preincubated for 15 mins followed by substrate addition mea...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 5C(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50153093(CHEMBL3775668)
Affinity DataIC50: 46nMAssay Description:Inhibition of KDM5C (unknown origin) using biotin-H3K4me3 as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 4A(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50153093(CHEMBL3775668)
Affinity DataIC50: 143nMAssay Description:Inhibition of human N-terminal His-tagged KDM4A (1 to 359 residues) expressed in Escherichia coli using biotin-H3K9me3 as substrate preincubated for ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 4B(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50153093(CHEMBL3775668)
Affinity DataIC50: 29nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged KDM4B (1 to 500 residues) expressed in baculovirus infected sf9 cells using biotin-H3K9me3 as s...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 2A(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50153093(CHEMBL3775668)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of KDM2A (unknown origin) using biotin-H3K36me2 (28 to 48 residues) as substrate preincubated for 15 mins followed by substrate addition m...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 5B(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50153093(CHEMBL3775668)
Affinity DataIC50: 26nMAssay Description:Inhibition of KDM5B (unknown origin) using biotin-H3K4me3 as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed