BDBM50152743 CHEMBL3781308

SMILES COc1ccccc1N1CCN(CC1C)c1ncnc2n(ncc12)-c1ccccc1

InChI Key InChIKey=MTIZOXXUAPPZTG-UHFFFAOYSA-N

Data  3 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50152743   

TargetSolute carrier family 2, facilitated glucose transporter member 1(Human)
Bayer Pharma

Curated by ChEMBL

LigandBDBM50152743(CHEMBL3781308)Copy SMILESCopy InChI

Affinity DataIC50: 14nMAssay Description:Inhibition of human GLUT1 expressed in DLD1 cells assessed as ATP production co-incubated with 100 mM glucose for 16 hrs by CellTiter-Glo assay in pr...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
7/2/2017
Entry Details Article
Copy Entry DOIPubMed
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TargetSolute carrier family 2, facilitated glucose transporter member 3(Human)
Bayer Pharma

Curated by ChEMBL

LigandBDBM50152743(CHEMBL3781308)Copy SMILESCopy InChI

Affinity DataIC50: 120nMAssay Description:Inhibition of human GLUT3 expressed in GLUT1 knock-out DLD1 cells assessed as ATP production co-incubated with 300 mM glucose for 16 hrs by CellTiter...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
7/2/2017
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL

TargetSolute carrier family 2, facilitated glucose transporter member 2(Human)
Bayer Pharma

Curated by ChEMBL

LigandBDBM50152743(CHEMBL3781308)Copy SMILESCopy InChI

Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of human GLUT2 expressed in CHO cells assessed as ATP production co-incubated with 30 mM fructose for 16 hrs by CellTiter-Glo assay in pre...More data for this Ligand-Target Pair

Target InfoKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
7/2/2017
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL