BDBM50152559 4-Biphenyl-4-yl-2,4-dioxo-butyric acid::CHEMBL1829211::CHEMBL274003

SMILES OC(=O)C(=O)CC(=O)c1ccc(cc1)-c1ccccc1

InChI Key InChIKey=OCTADEKBEAHCGJ-UHFFFAOYSA-N

Data  1 KI  4 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50152559   

TargetFlap endonuclease 1(Human)
Athersys

Curated by ChEMBL
LigandPNGBDBM50152559(CHEMBL274003 | CHEMBL1829211 | 4-Biphenyl-4-yl-2,4...)
Affinity DataIC50: 3.50E+3nMAssay Description:Concentration required for 50% inhibition of Flap endonuclease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA excision repair protein ERCC-5(Human)
Athersys

Curated by ChEMBL
LigandPNGBDBM50152559(CHEMBL274003 | CHEMBL1829211 | 4-Biphenyl-4-yl-2,4...)
Affinity DataIC50: 1.60E+3nMAssay Description:Concentration required for 50% inhibition of Xeroderma pigmentosum GMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target2-Hydroxyacid oxidase 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50152559(CHEMBL274003 | CHEMBL1829211 | 4-Biphenyl-4-yl-2,4...)
Affinity DataIC50: 1.10E+3nMAssay Description:In vitro inhibition of porcine Glycolate oxidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetPolymerase acidic protein(Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)
University of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM50152559(CHEMBL274003 | CHEMBL1829211 | 4-Biphenyl-4-yl-2,4...)
Affinity DataEC50:  3.56E+3nMAssay Description:Plaque growth inhibitionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetPolymerase acidic protein(Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)
University of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM50152559(CHEMBL274003 | CHEMBL1829211 | 4-Biphenyl-4-yl-2,4...)
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of cap 1 ALMV primed Influenza transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetPolymerase acidic protein(Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)
University of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM50152559(CHEMBL274003 | CHEMBL1829211 | 4-Biphenyl-4-yl-2,4...)
Affinity DataKi:  960nMAssay Description:Binding affinity to PA N-terminal domain (Competitive)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed