BDBM50152329 1-(4-nonylbenzyl)pyrrolidin-3-ylphosphonic acid::CHEMBL184349::[1-(4-Nonyl-benzyl)-pyrrolidin-3-yl]-phosphonic acid

SMILES CCCCCCCCCc1ccc(CN2CCC(C2)P(O)(O)=O)cc1

InChI Key InChIKey=PRUUCTGBHIGGOH-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50152329   

TargetSphingosine 1-phosphate receptor 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50152329([1-(4-Nonyl-benzyl)-pyrrolidin-3-yl]-phosphonic ac...)
Affinity DataIC50: 45nMAssay Description:Displacement of [33P]sphingosine 1 phosphate from human S1P4 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50152329([1-(4-Nonyl-benzyl)-pyrrolidin-3-yl]-phosphonic ac...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [33P]sphingosine 1 phosphate from human S1P2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50152329([1-(4-Nonyl-benzyl)-pyrrolidin-3-yl]-phosphonic ac...)
Affinity DataIC50: 220nMAssay Description:Displacement of [33P]sphingosine 1 phosphate from human S1P3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50152329([1-(4-Nonyl-benzyl)-pyrrolidin-3-yl]-phosphonic ac...)
Affinity DataIC50: 6.90nMAssay Description:Displacement of [33P]sphingosine 1 phosphate from human S1P1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50152329([1-(4-Nonyl-benzyl)-pyrrolidin-3-yl]-phosphonic ac...)
Affinity DataIC50: 6.30nMAssay Description:Displacement of [33P]sphingosine 1 phosphate from human S1P5 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50152329([1-(4-Nonyl-benzyl)-pyrrolidin-3-yl]-phosphonic ac...)
Affinity DataIC50: 0.330nMAssay Description:Inhibition of [33P]-S1P binding to human Sphingosine 1-phosphate receptor 1 expressed on CHO cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50152329([1-(4-Nonyl-benzyl)-pyrrolidin-3-yl]-phosphonic ac...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of [33P]-S1P binding to human Sphingosine 1-phosphate receptor 2 expressed on CHO cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50152329([1-(4-Nonyl-benzyl)-pyrrolidin-3-yl]-phosphonic ac...)
Affinity DataIC50: 18nMAssay Description:Inhibition of [33P]-S1P binding to human Sphingosine 1-phosphate receptor 3 expressed on CHO cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50152329([1-(4-Nonyl-benzyl)-pyrrolidin-3-yl]-phosphonic ac...)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of [33P]-S1P binding to human Sphingosine 1-phosphate receptor 5 expressed on CHO cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50152329([1-(4-Nonyl-benzyl)-pyrrolidin-3-yl]-phosphonic ac...)
Affinity DataIC50: 86nMAssay Description:Inhibition of [33P]-S1P binding to human Sphingosine 1-phosphate receptor 4 expressed on CHO cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed