BDBM50152014 4-{4-[4-(5-Cyano-1H-indol-3-yl)-butyl]-piperazin-1-yl}-benzamide::CHEMBL187909

SMILES NC(=O)c1ccc(cc1)N1CCN(CCCCc2c[nH]c3ccc(cc23)C#N)CC1

InChI Key InChIKey=VCIWMQRQRVRAAL-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50152014   

TargetD(2) dopamine receptor(Rat)
Merck

Curated by ChEMBL
LigandPNGBDBM50152014(4-{4-[4-(5-Cyano-1H-indol-3-yl)-butyl]-piperazin-1...)
Affinity DataIC50: 270nMAssay Description:Displacement of [3H]spiperone from dopamine D2 receptor of rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Merck

Curated by ChEMBL
LigandPNGBDBM50152014(4-{4-[4-(5-Cyano-1H-indol-3-yl)-butyl]-piperazin-1...)
Affinity DataIC50: 118nMAssay Description:Inhibition of 8-OH DPAT binding to rat hydroxytryptamine 1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50152014(4-{4-[4-(5-Cyano-1H-indol-3-yl)-butyl]-piperazin-1...)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of [3H]5-HT re-uptake in rat synaptosomesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed