BDBM50151990 3-[4-(4-{2-Cyano-3-[2-(2-ethoxy-ethoxy)-ethoxy]-phenyl}-piperazin-1-yl)-butyl]-1H-indole-5-carbonitrile::CHEMBL186468

SMILES CCOCCOCCOc1cccc(N2CCN(CCCCc3c[nH]c4ccc(cc34)C#N)CC2)c1C#N

InChI Key InChIKey=KAWWVHKWESRAHV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50151990   

TargetD(2) dopamine receptor(Rat)
Merck

Curated by ChEMBL
LigandPNGBDBM50151990(3-[4-(4-{2-Cyano-3-[2-(2-ethoxy-ethoxy)-ethoxy]-ph...)
Affinity DataIC50: 28nMAssay Description:Displacement of [3H]spiperone from dopamine D2 receptor of rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Merck

Curated by ChEMBL
LigandPNGBDBM50151990(3-[4-(4-{2-Cyano-3-[2-(2-ethoxy-ethoxy)-ethoxy]-ph...)
Affinity DataIC50: 2nMAssay Description:Inhibition of 8-OH DPAT binding to rat hydroxytryptamine 1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50151990(3-[4-(4-{2-Cyano-3-[2-(2-ethoxy-ethoxy)-ethoxy]-ph...)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of [3H]5-HT re-uptake in rat synaptosomesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed