BDBM50151748 3-Hydroxy-4-[4-(2-methyl-benzyloxy)-benzenesulfonyl]-tetrahydro-pyran-3-carboxylic acid hydroxyamide::CHEMBL183935

SMILES Cc1ccccc1COc1ccc(cc1)S(=O)(=O)[C@@H]1CCOC[C@]1(O)C(=O)NO

InChI Key InChIKey=XWNLDJDYIDRBJI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50151748   

LigandPNGBDBM50151748(3-Hydroxy-4-[4-(2-methyl-benzyloxy)-benzenesulfony...)
Affinity DataIC50: 55nMAssay Description:Inhibitory concentration against aggrecanaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50151748(3-Hydroxy-4-[4-(2-methyl-benzyloxy)-benzenesulfony...)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibitory concentration against matrix metalloprotease 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50151748(3-Hydroxy-4-[4-(2-methyl-benzyloxy)-benzenesulfony...)
Affinity DataIC50: 21nMAssay Description:Inhibitory concentration against matrix metalloprotease 13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed