BDBM50151746 4-[4-(3-Chloro-benzyloxy)-benzenesulfonyl]-3-hydroxy-tetrahydro-pyran-3-carboxylic acid hydroxyamide::CHEMBL184065

SMILES ONC(=O)[C@@]1(O)COCC[C@H]1S(=O)(=O)c1ccc(OCc2cccc(Cl)c2)cc1

InChI Key InChIKey=OUHOPXMPDCBZLB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50151746   

LigandPNGBDBM50151746(4-[4-(3-Chloro-benzyloxy)-benzenesulfonyl]-3-hydro...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory concentration against aggrecanaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50151746(4-[4-(3-Chloro-benzyloxy)-benzenesulfonyl]-3-hydro...)
Affinity DataIC50: 7.90E+3nMAssay Description:Inhibitory concentration against matrix metalloprotease 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50151746(4-[4-(3-Chloro-benzyloxy)-benzenesulfonyl]-3-hydro...)
Affinity DataIC50: 2.40nMAssay Description:Inhibitory concentration against matrix metalloprotease 13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed