BDBM50151743 (3S,4R)-4-[4-(2,3-Dichloro-benzyloxy)-benzenesulfonyl]-3-hydroxy-tetrahydro-pyran-3-carboxylic acid hydroxyamide::CHEMBL183886

SMILES ONC(=O)[C@@]1(O)COCC[C@H]1S(=O)(=O)c1ccc(OCc2cccc(Cl)c2Cl)cc1

InChI Key InChIKey=SPZLSWDAZSYJAK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50151743   

LigandPNGBDBM50151743((3S,4R)-4-[4-(2,3-Dichloro-benzyloxy)-benzenesulfo...)
Affinity DataIC50: 140nMAssay Description:Inhibitory concentration against aggrecanaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50151743((3S,4R)-4-[4-(2,3-Dichloro-benzyloxy)-benzenesulfo...)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibitory concentration against matrix metalloprotease 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50151743((3S,4R)-4-[4-(2,3-Dichloro-benzyloxy)-benzenesulfo...)
Affinity DataIC50: 15nMAssay Description:Inhibitory concentration against matrix metalloprotease 13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed