BDBM50151742 (3S,4R)-3-Hydroxy-4-(2''-methyl-biphenyl-4-sulfonyl)-tetrahydro-pyran-3-carboxylic acid hydroxyamide::CHEMBL364574

SMILES Cc1ccccc1-c1ccc(cc1)S(=O)(=O)[C@@H]1CCOC[C@]1(O)C(=O)NO

InChI Key InChIKey=LUTKRKPVCCDDOR-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50151742   

LigandPNGBDBM50151742((3S,4R)-3-Hydroxy-4-(2''-methyl-biphenyl-4-sulfony...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory concentration against aggrecanaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50151742((3S,4R)-3-Hydroxy-4-(2''-methyl-biphenyl-4-sulfony...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory concentration against matrix metalloprotease 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50151742((3S,4R)-3-Hydroxy-4-(2''-methyl-biphenyl-4-sulfony...)
Affinity DataIC50: 140nMAssay Description:Inhibitory concentration against matrix metalloprotease 13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed