BDBM50151739 4-[4-(2,5-Dimethyl-benzyloxy)-benzenesulfonyl]-3-hydroxy-tetrahydro-pyran-3-carboxylic acid hydroxyamide::CHEMBL182880

SMILES Cc1ccc(C)c(COc2ccc(cc2)S(=O)(=O)[C@@H]2CCOC[C@]2(O)C(=O)NO)c1

InChI Key InChIKey=NXFDHNJDXVCAMS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50151739   

LigandPNGBDBM50151739(4-[4-(2,5-Dimethyl-benzyloxy)-benzenesulfonyl]-3-h...)
Affinity DataIC50: 26nMAssay Description:Inhibitory concentration against aggrecanaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50151739(4-[4-(2,5-Dimethyl-benzyloxy)-benzenesulfonyl]-3-h...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibitory concentration against matrix metalloprotease 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50151739(4-[4-(2,5-Dimethyl-benzyloxy)-benzenesulfonyl]-3-h...)
Affinity DataIC50: 300nMAssay Description:Inhibitory concentration against matrix metalloprotease 13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed