BDBM50151737 3-Hydroxy-4-[4-(2-trifluoromethyl-benzyloxy)-benzenesulfonyl]-tetrahydro-pyran-3-carboxylic acid hydroxyamide::CHEMBL182273

SMILES ONC(=O)[C@@]1(O)COCC[C@H]1S(=O)(=O)c1ccc(OCc2ccccc2C(F)(F)F)cc1

InChI Key InChIKey=FNCXJJHZBHAVJZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50151737   

LigandPNGBDBM50151737(3-Hydroxy-4-[4-(2-trifluoromethyl-benzyloxy)-benze...)
Affinity DataIC50: 220nMAssay Description:Inhibitory concentration against aggrecanaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50151737(3-Hydroxy-4-[4-(2-trifluoromethyl-benzyloxy)-benze...)
Affinity DataIC50: 28nMAssay Description:Inhibitory concentration against matrix metalloprotease 13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50151737(3-Hydroxy-4-[4-(2-trifluoromethyl-benzyloxy)-benze...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibitory concentration against matrix metalloprotease 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed