BDBM50151519 4-[[1-(3-Chloro-benzyl)-4-(3-chloro-phenyl)-6-oxo-1,6-dihydro-pyridin-3-ylmethoxy]-(3-methyl-3H-imidazol-4-yl)-methyl]-benzonitrile::CHEMBL363518

SMILES Cn1cncc1C(OCc1cn(Cc2cccc(Cl)c2)c(=O)cc1-c1cccc(Cl)c1)c1ccc(cc1)C#N

InChI Key InChIKey=ZNCWTFCMFYQTSV-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50151519   

LigandPNGBDBM50151519(4-[[1-(3-Chloro-benzyl)-4-(3-chloro-phenyl)-6-oxo-...)
Affinity DataIC50: 1.20E+3nMAssay Description:inhibitory concentration needed to to reduce the bovine GGTase-catalyzed incorporation of [3H]-FPP into a biotin-linked K-ras (B) decapeptideMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50151519(4-[[1-(3-Chloro-benzyl)-4-(3-chloro-phenyl)-6-oxo-...)
Affinity DataEC50:  10nMAssay Description:Reduced farnesylation of H-ras transformed NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed