BDBM50151359 4-(5-Methyl-pyridin-2-yl)-5-quinolin-4-yl-thiazol-2-ylamine::CHEMBL359611

SMILES Cc1ccc(nc1)-c1nc(N)sc1-c1ccnc2ccccc12

InChI Key InChIKey=USWZUNDOUGZOOF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50151359   

TargetTGF-beta receptor type-1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50151359(4-(5-Methyl-pyridin-2-yl)-5-quinolin-4-yl-thiazol-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity for Activin A receptor type II-like kinase (ALK5) in fluorescence polarization binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50151359(4-(5-Methyl-pyridin-2-yl)-5-quinolin-4-yl-thiazol-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Stimulation of Transforming growth factor beta receptor I kinase in HepG2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed