BDBM50151351 5''-Quinolin-4-yl-[2,4'']bithiazolyl-2''-ylamine::5'-(quinolin-4-yl)-2,4'-bithiazol-2'-amine::CHEMBL362710

SMILES Nc1nc(-c2nccs2)c(s1)-c1ccnc2ccccc12

InChI Key InChIKey=JHZIIPPDVRVCNU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50151351   

TargetTGF-beta receptor type-1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50151351(5''-Quinolin-4-yl-[2,4'']bithiazolyl-2''-ylamine |...)
Affinity DataIC50: 1.17E+3nMAssay Description:Binding affinity to Activin A receptor type II-like kinase (ALK5) in fluorescence polarization binding assay; Range is (0.783-1.764)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50151351(5''-Quinolin-4-yl-[2,4'']bithiazolyl-2''-ylamine |...)
Affinity DataIC50: 6.58E+3nMAssay Description:Stimulation of Transforming growth factor beta receptor I kinase in HepG2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50151351(5''-Quinolin-4-yl-[2,4'']bithiazolyl-2''-ylamine |...)
Affinity DataIC50: 1.18E+3nMAssay Description:Inhibition of TGFR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed