BDBM50151057 CHEMBL3770726

SMILES O=C(N[C@H]1CNC1=O)OCCCCC1CCCCC1

InChI Key InChIKey=FNLUJRBWJBUJTC-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50151057   

TargetN-acylethanolamine-hydrolyzing acid amidase(Human)
Italian Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50151057(CHEMBL3770726)
Affinity DataIC50: 73nMAssay Description:Inhibition of human NAAA expressed in HEK293 cells preincubated for 10 mins followed by N-(4-methyl-2-oxo-chromen-7-yl)-hexadecanamide substrate addi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2017
Entry Details Article
PubMed
TargetN-acylethanolamine-hydrolyzing acid amidase(Human)
Italian Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50151057(CHEMBL3770726)
Affinity DataIC50: 27nMAssay Description:Inhibition of recombinant human NAAA expressed in HEK293 cells after 30 mins by UPLC/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2017
Entry Details Article
PubMed
TargetAcid ceramidase(Human)
Italian Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50151057(CHEMBL3770726)
Affinity DataIC50: 6.27E+3nMAssay Description:Inhibition of human acid ceramidase by UPLC/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2017
Entry Details Article
PubMed
TargetN-acylethanolamine-hydrolyzing acid amidase(Rat)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50151057(CHEMBL3770726)
Affinity DataIC50: 28nMAssay Description:Inhibition of rat NAAA expressed in HEK cells after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2019
Entry Details Article
PubMed
TargetN-acylethanolamine-hydrolyzing acid amidase(Human)
Italian Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50151057(CHEMBL3770726)
Affinity DataIC50: 73nMAssay Description:Inhibition of recombinant human NAAA expressed in HEK cells after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2019
Entry Details Article
PubMed
TargetN-acylethanolamine-hydrolyzing acid amidase(Human)
Italian Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50151057(CHEMBL3770726)
Affinity DataIC50: 27nMAssay Description:Inhibition recombinant human NAAA expressed in HEK293 cells after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetN-acylethanolamine-hydrolyzing acid amidase(Rat)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50151057(CHEMBL3770726)
Affinity DataIC50: 63nMAssay Description:Inhibition of recombinant Sprague-Dawley rat NAAA expressed in HEK293 cells after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetN-acylethanolamine-hydrolyzing acid amidase(Human)
Italian Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50151057(CHEMBL3770726)
Affinity DataIC50: 27nMAssay Description:Inhibition of recombinant human NAAA expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetN-acylethanolamine-hydrolyzing acid amidase(Human)
Italian Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50151057(CHEMBL3770726)
Affinity DataIC50: 6nMAssay Description:Inhibition of human NAAAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetN-acylethanolamine-hydrolyzing acid amidase(Rat)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50151057(CHEMBL3770726)
Affinity DataIC50: 13nMAssay Description:Inhibition of rat NAAAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed