BDBM50150818 CHEMBL3774575
SMILES CCCOc1cc(OCCCCN(C)C)cc(Oc2cc3n(C)c(=O)n(C)c3cc2NS(=O)(=O)c2ccc(OC)c(OC)c2)c1
InChI Key InChIKey=HYQBRUSSCIAOOD-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 13 hits for monomerid = 50150818
TargetTranscription intermediary factor 1-alpha(Human)
The University of Texas M.D. Anderson Cancer Center
Curated by ChEMBL
The University of Texas M.D. Anderson Cancer Center
Curated by ChEMBL
Affinity DataIC50: 7.60nMAssay Description:Inhibition of recombinant human His-tagged TRIM24-PHD/bromodomain expressed in Escherichia coli strains BL21 (DE3) cells using biotinylated H3K23ac (...More data for this Ligand-Target Pair
3D Structure (crystal)TargetTranscription intermediary factor 1-alpha(Human)
The University of Texas M.D. Anderson Cancer Center
Curated by ChEMBL
The University of Texas M.D. Anderson Cancer Center
Curated by ChEMBL
Affinity DataKd: 31nMAssay Description:Binding affinity to recombinant human His-tagged TRIM24-PHD/bromodomain expressed in Escherichia coli strains BL21 (DE3) cells by isothermal titratio...More data for this Ligand-Target Pair
Affinity DataKd: 14nMAssay Description:Binding affinity to BRPF1 (unknown origin) expressed in Escherichia coli strains BL21 (DE3) cells by isothermal titration calorimetryMore data for this Ligand-Target Pair
TargetTranscription intermediary factor 1-alpha(Human)
The University of Texas M.D. Anderson Cancer Center
Curated by ChEMBL
The University of Texas M.D. Anderson Cancer Center
Curated by ChEMBL
Affinity DataKd: 1.30nMAssay Description:Binding affinity to recombinant human TRIM24-PHD/bromodomain expressed in bacterial system by bromoscan assayMore data for this Ligand-Target Pair
Affinity DataKd: 2.10nMAssay Description:Binding affinity to recombinant human BRPF1 expressed in bacterial system by bromoscan assayMore data for this Ligand-Target Pair
TargetBromodomain-containing protein 1(Human)
The University of Texas M.D. Anderson Cancer Center
Curated by ChEMBL
The University of Texas M.D. Anderson Cancer Center
Curated by ChEMBL
Affinity DataKd: 12nMAssay Description:Binding affinity to recombinant human BRPF2 expressed in bacterial system by bromoscan assayMore data for this Ligand-Target Pair
TargetBromodomain and PHD finger-containing protein 3(Human)
The University of Texas M.D. Anderson Cancer Center
Curated by ChEMBL
The University of Texas M.D. Anderson Cancer Center
Curated by ChEMBL
Affinity DataKd: 27nMAssay Description:Binding affinity to recombinant human BRPF3 expressed in bacterial system by bromoscan assayMore data for this Ligand-Target Pair
TargetBromodomain adjacent to zinc finger domain protein 2B(Human)
The University of Texas M.D. Anderson Cancer Center
Curated by ChEMBL
The University of Texas M.D. Anderson Cancer Center
Curated by ChEMBL
Affinity DataKd: 400nMAssay Description:Binding affinity to recombinant human BAZ2B expressed in bacterial system by bromoscan assayMore data for this Ligand-Target Pair
TargetTranscription initiation factor TFIID subunit 1(Human)
The University of Texas M.D. Anderson Cancer Center
Curated by ChEMBL
The University of Texas M.D. Anderson Cancer Center
Curated by ChEMBL
Affinity DataKd: 1.80E+3nMAssay Description:Binding affinity to recombinant human TAF1 bromodomain 2 expressed in bacterial system by bromoscan assayMore data for this Ligand-Target Pair
TargetBromodomain-containing protein 4(Human)
The University of Texas M.D. Anderson Cancer Center
Curated by ChEMBL
The University of Texas M.D. Anderson Cancer Center
Curated by ChEMBL
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to recombinant human BRD4 long isoform bromodomain 1 expressed in bacterial system by bromoscan assayMore data for this Ligand-Target Pair
TargetBromodomain-containing protein 4(Human)
The University of Texas M.D. Anderson Cancer Center
Curated by ChEMBL
The University of Texas M.D. Anderson Cancer Center
Curated by ChEMBL
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to recombinant human BRD4 long isoform bromodomain 2 expressed in bacterial system by bromoscan assayMore data for this Ligand-Target Pair
TargetTranscription intermediary factor 1-alpha(Human)
The University of Texas M.D. Anderson Cancer Center
Curated by ChEMBL
The University of Texas M.D. Anderson Cancer Center
Curated by ChEMBL
Affinity DataEC50: 50nMAssay Description:Inhibition of Flag-tagged TRIM24-PHD/bromodomain (unknown origin) expressed in human HeLa cells for 2 hrs by AlphaLisa assayMore data for this Ligand-Target Pair
TargetTranscription intermediary factor 1-alpha(Human)
The University of Texas M.D. Anderson Cancer Center
Curated by ChEMBL
The University of Texas M.D. Anderson Cancer Center
Curated by ChEMBL
Affinity DataIC50: 150nMAssay Description:Inhibition of TRIM24 (unknown origin) measured alphascreen assayMore data for this Ligand-Target Pair