BDBM50150673 CHEMBL363466::[(S)-5-(2,6-Dimethoxy-phenyl)-1,2,3,4-tetrahydro-naphthalen-2-yl]-dimethyl-amine

SMILES COc1cccc(OC)c1-c1cccc2C[C@H](CCc12)N(C)C

InChI Key InChIKey=BFHVQDBLFZYJPG-UHFFFAOYSA-N

Data  6 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50150673   

Target5-hydroxytryptamine receptor 6(Rat)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50150673([(S)-5-(2,6-Dimethoxy-phenyl)-1,2,3,4-tetrahydro-n...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of [3H]5-HT binding to rat 5-HT6 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50150673([(S)-5-(2,6-Dimethoxy-phenyl)-1,2,3,4-tetrahydro-n...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of [3H]GR-65630 binding to rabbit ileum muscularis 5-HT3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Guinea pig)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50150673([(S)-5-(2,6-Dimethoxy-phenyl)-1,2,3,4-tetrahydro-n...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of [3H]- GR-113808 binding to guinea pig striatum 5-HT4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50150673([(S)-5-(2,6-Dimethoxy-phenyl)-1,2,3,4-tetrahydro-n...)
Affinity DataKi:  2.55nMAssay Description:Inhibition of [3H]-5-HT binding to rat 5-hydroxytryptamine 7 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50150673([(S)-5-(2,6-Dimethoxy-phenyl)-1,2,3,4-tetrahydro-n...)
Affinity DataKi:  2.55nMAssay Description:Inhibition of [3H]5-HT binding to rat 5-HT7 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50150673([(S)-5-(2,6-Dimethoxy-phenyl)-1,2,3,4-tetrahydro-n...)
Affinity DataKi:  241nMAssay Description:Inhibition of [3H]raclopride binding to human dopamine D2A receptor expressed in Ltk cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50150673([(S)-5-(2,6-Dimethoxy-phenyl)-1,2,3,4-tetrahydro-n...)
Affinity DataKi:  241nMAssay Description:Inhibition of [3H]raclopride binding to Dopamine receptor D2A in ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50150673([(S)-5-(2,6-Dimethoxy-phenyl)-1,2,3,4-tetrahydro-n...)
Affinity DataKi:  1.42E+3nMAssay Description:Inhibition of [3H]8-OH-DPAT binding to human 5-HT1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50150673([(S)-5-(2,6-Dimethoxy-phenyl)-1,2,3,4-tetrahydro-n...)
Affinity DataKi:  1.42E+3nMAssay Description:Inhibition of [3H]8-OH-DPAT binding to rat 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed