BDBM50149846 2''-Amino-6''-(2-cyclopropylmethoxy-6-hydroxy-phenyl)-1,2,3,4,5,6-hexahydro-[3,4'']bipyridinyl-3''-carbonitrile::CHEMBL182407

SMILES Nc1nc(cc(C2CCCNC2)c1C#N)-c1c(O)cccc1OCC1CC1

InChI Key InChIKey=LRAIEGOIIAZHRP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50149846   

LigandPNGBDBM50149846(2''-Amino-6''-(2-cyclopropylmethoxy-6-hydroxy-phen...)
Affinity DataIC50: 3nMAssay Description:Inhibition of recombinant human I-kappa-B-kinase beta (IKK beta)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50149846(2''-Amino-6''-(2-cyclopropylmethoxy-6-hydroxy-phen...)
Affinity DataIC50: 3nMAssay Description:Inhibition of human IKK-beta using TMB as substrate after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
LigandPNGBDBM50149846(2''-Amino-6''-(2-cyclopropylmethoxy-6-hydroxy-phen...)
Affinity DataIC50: 3nMAssay Description:Inhibition of human IKKbeta using GST-IkappaBalpha as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed