BDBM50149830 2-Amino-6-(2-heptyloxy-6-hydroxy-phenyl)-1'',2'',3'',4'',5'',6''-hexahydro-[4,4'']bipyridinyl-3-carbonitrile::CHEMBL185509

SMILES CCCCCCCOc1cccc(O)c1-c1cc(C2CCNCC2)c(C#N)c(N)n1

InChI Key InChIKey=CHGDFHFPFZBZLC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50149830   

LigandPNGBDBM50149830(2-Amino-6-(2-heptyloxy-6-hydroxy-phenyl)-1'',2'',3...)
Affinity DataIC50: 50nMAssay Description:Inhibition of recombinant human I-kappa-B-kinase beta (IKK beta)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50149830(2-Amino-6-(2-heptyloxy-6-hydroxy-phenyl)-1'',2'',3...)
Affinity DataIC50: 50nMAssay Description:Inhibition of human IKK-beta using TMB as substrate after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
LigandPNGBDBM50149830(2-Amino-6-(2-heptyloxy-6-hydroxy-phenyl)-1'',2'',3...)
Affinity DataIC50: 50nMAssay Description:Inhibition of human IKKbeta using GST-IkappaBalpha as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed