BDBM50149815 2-Amino-4-(1-amino-2-phenyl-ethyl)-6-(2-hydroxy-phenyl)-nicotinonitrile::CHEMBL182282

SMILES NC(Cc1ccccc1)c1cc(nc(N)c1C#N)-c1ccccc1O

InChI Key InChIKey=FXHAOHCSGZLTCZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50149815   

LigandPNGBDBM50149815(2-Amino-4-(1-amino-2-phenyl-ethyl)-6-(2-hydroxy-ph...)
Affinity DataIC50: 60nMAssay Description:Inhibitory activity against recombinant human I-kappa-B-kinase betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50149815(2-Amino-4-(1-amino-2-phenyl-ethyl)-6-(2-hydroxy-ph...)
Affinity DataIC50: 60nMAssay Description:Inhibition of recombinant human I-kappa-B-kinase beta (IKK beta)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50149815(2-Amino-4-(1-amino-2-phenyl-ethyl)-6-(2-hydroxy-ph...)
Affinity DataIC50: 60nMAssay Description:Inhibition of human IKK-beta using TMB as substrate after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed