BDBM50149122 2-(4-Bromo-phenyl)-5-butyl-[1,2,4]triazolo[1,5-c]quinazoline::CHEMBL339066

SMILES CCCCc1nc2ccccc2c2nc(nn12)-c1ccc(Br)cc1

InChI Key InChIKey=WCRWQPZNNMWWDZ-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50149122   

TargetAdenosine receptor A3(Human)
Otsuka Pharmaceutical Factory

Curated by ChEMBL
LigandPNGBDBM50149122(2-(4-Bromo-phenyl)-5-butyl-[1,2,4]triazolo[1,5-c]q...)
Affinity DataIC50: 8.20nMAssay Description:Displacement of specific [125I]AB-MECA binding at human adenosine A3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Otsuka Pharmaceutical Factory

Curated by ChEMBL
LigandPNGBDBM50149122(2-(4-Bromo-phenyl)-5-butyl-[1,2,4]triazolo[1,5-c]q...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of specific [3H]-CGS- 21680 binding at human adenosine A2A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Otsuka Pharmaceutical Factory

Curated by ChEMBL
LigandPNGBDBM50149122(2-(4-Bromo-phenyl)-5-butyl-[1,2,4]triazolo[1,5-c]q...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of specific [3H]DPCPX binding at human adenosine A1 receptor expressed in CHO cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
Otsuka Pharmaceutical Factory

Curated by ChEMBL
LigandPNGBDBM50149122(2-(4-Bromo-phenyl)-5-butyl-[1,2,4]triazolo[1,5-c]q...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of specific [3H]DPCPX binding at human adenosine A2B receptor expressed in HEK293 cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
Otsuka Pharmaceutical Factory

Curated by ChEMBL
LigandPNGBDBM50149122(2-(4-Bromo-phenyl)-5-butyl-[1,2,4]triazolo[1,5-c]q...)
Affinity DataIC50: 8.20nMAssay Description:Displacement of [125I]I-AB-MECA from human recombinant adenosine A3 receptor expressed in CHO cells after 60 mins by gamma counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Otsuka Pharmaceutical Factory

Curated by ChEMBL
LigandPNGBDBM50149122(2-(4-Bromo-phenyl)-5-butyl-[1,2,4]triazolo[1,5-c]q...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]CGS21680 from human recombinant adenosine A2A receptor expressed in CHO cells after 60 mins by gamma counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Otsuka Pharmaceutical Factory

Curated by ChEMBL
LigandPNGBDBM50149122(2-(4-Bromo-phenyl)-5-butyl-[1,2,4]triazolo[1,5-c]q...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]CCPA from human recombinant adenosine A1 receptor expressed in CHO cells after 60 mins by gamma counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed