BDBM50148479 CHEMBL3770259

SMILES COc1ccc(Oc2cc3n(C)c(=O)n(C)c3cc2NS(=O)(=O)c2ccccc2)cc1

InChI Key InChIKey=KQJPZLNOKCNFSE-UHFFFAOYSA-N

Data  4 IC50

PDB links: 1 PDB ID matches this monomer.

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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50148479   

TargetTranscription intermediary factor 1-alpha(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50148479(CHEMBL3770259)
Affinity DataIC50: 730nMAssay Description:Inhibition of N-terminal His6-SUMO-1-tagged recombinant human TRIM24 bromodomain expressed in Escherichia coli BL21(DE3)-R3-pRARE2 cells by Alpha Scr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPeregrin(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50148479(CHEMBL3770259)
Affinity DataIC50: 660nMAssay Description:Inhibition of BRPF1B (unknown origin) by Alpha Screen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2017
Entry Details Article
PubMed
TargetBromodomain-containing protein 1(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50148479(CHEMBL3770259)
Affinity DataIC50: 2.77E+3nMAssay Description:Inhibition of BRPF2 BRD1 (unknown origin) by Alpha Screen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2017
Entry Details Article
PubMed
TargetTranscription intermediary factor 1-alpha(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50148479(CHEMBL3770259)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of recombinant human His-tagged TRIM24-PHD/bromodomain expressed in Escherichia coli strains BL21 (DE3) cells using biotinylated H3K23ac (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)