BDBM50147974 (S)-2-[2-((R)-1-Carbamimidoyl-piperidin-3-yl)-acetylamino]-3-(4-phenylethynyl-phenyl)-propionic acid methyl ester::2-[3-METHYL-4-(N-METHYL-GUANIDINO)-BUTYRYLAMINO]-3-(4-PHENYLETHYNYL-PHENYL)-PROPIONIC ACID METHYL ESTER::CHEMBL419362

SMILES COC(=O)[C@H](Cc1ccc(cc1)C#Cc1ccccc1)NC(=O)C[C@H]1CCCN(C1)C(N)=N

InChI Key InChIKey=MRNGXYMKYHNMLV-UHFFFAOYSA-N

Data  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50147974   

TargetInterleukin-2 receptor subunit alpha(Mouse)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50147974(2-[3-METHYL-4-(N-METHYL-GUANIDINO)-BUTYRYLAMINO]-3...)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of mouse Interleukin-2 receptor alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetInterleukin-2 receptor subunit alpha(Mouse)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50147974(2-[3-METHYL-4-(N-METHYL-GUANIDINO)-BUTYRYLAMINO]-3...)
Affinity DataEC50:  1.00E+5nMAssay Description:Effective concentration required against phosphorylation of Mammary gland factor/STAT5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
LigandPNGBDBM50147974(2-[3-METHYL-4-(N-METHYL-GUANIDINO)-BUTYRYLAMINO]-3...)
Affinity DataIC50: 6.00E+3nMAssay Description:Competitive inhibition of IL2 receptor alpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article

LigandPNGBDBM50147974(2-[3-METHYL-4-(N-METHYL-GUANIDINO)-BUTYRYLAMINO]-3...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of IL-2R alpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed