BDBM50147534 1,3-Dioxo-2-[3-(5-phenyl-benzooxazol-2-yl)-4-propylamino-phenyl]-indan-5-carboxylic acid::1,3-dioxo-2-(3-(5-phenylbenzo[d]oxazol-2-yl)-4-(propylamino)phenyl)isoindoline-5-carboxylic acid::CHEMBL109657

SMILES CCCNc1ccc(cc1-c1nc2cc(ccc2o1)-c1ccccc1)N1C(=O)c2ccc(cc2C1=O)C(O)=O

InChI Key InChIKey=PURUNRMSWAQLDE-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50147534   

TargetHeparanase(Human)
Celltech R&D

Curated by ChEMBL
LigandPNGBDBM50147534(1,3-dioxo-2-(3-(5-phenylbenzo[d]oxazol-2-yl)-4-(pr...)
Affinity DataIC50: 250nMAssay Description:In vivo inhibitory activity against human HeparanaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHeparanase(Human)
Celltech R&D

Curated by ChEMBL
LigandPNGBDBM50147534(1,3-dioxo-2-(3-(5-phenylbenzo[d]oxazol-2-yl)-4-(pr...)
Affinity DataIC50: 251nMAssay Description:Inhibition of heparanaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetHeparanase(Human)
Celltech R&D

Curated by ChEMBL
LigandPNGBDBM50147534(1,3-dioxo-2-(3-(5-phenylbenzo[d]oxazol-2-yl)-4-(pr...)
Affinity DataIC50: 250nMAssay Description:Inhibition of human recombinant HeparanaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetHeparanase(Human)
Celltech R&D

Curated by ChEMBL
LigandPNGBDBM50147534(1,3-dioxo-2-(3-(5-phenylbenzo[d]oxazol-2-yl)-4-(pr...)
Affinity DataIC50: 250nMAssay Description:Inhibition of human heparanase assessed as reduction in basic fibroblast growth factor binding incubated for 2 hrs by microplate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed