BDBM50147253 2-(4-(3-fluorophenyl)piperidine-1-carbonyl)-4-isopropyl-3-methylisoxazol-5(2H)-one::2-[4-(3-Fluoro-phenyl)-piperidine-1-carbonyl]-4-isopropyl-3-methyl-2H-isoxazol-5-one::CHEMBL108523

SMILES CC(C)c1c(C)n(oc1=O)C(=O)N1CCC(CC1)c1cccc(F)c1

InChI Key InChIKey=IWNUMAPXFIGMJU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50147253   

TargetHormone-sensitive lipase(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50147253(2-[4-(3-Fluoro-phenyl)-piperidine-1-carbonyl]-4-is...)
Affinity DataIC50: 4nMAssay Description:Inhibition of forskolin-stimulated lipolysis in differentiated 3T3-L1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHormone-sensitive lipase(Rat)
University of Jordan

Curated by ChEMBL
LigandPNGBDBM50147253(2-[4-(3-Fluoro-phenyl)-piperidine-1-carbonyl]-4-is...)
Affinity DataIC50: 12nMAssay Description:Inhibition of HSL in Wistar rat isolated fat cells by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHormone-sensitive lipase(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50147253(2-[4-(3-Fluoro-phenyl)-piperidine-1-carbonyl]-4-is...)
Affinity DataIC50: 12nMAssay Description:Inhibition of human recombinant hormone sensitive lipase (HSL)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed