BDBM50147212 CHEMBL3765311::US11053243, Example 192
SMILES COC(=O)N[C@@H](C(C)C)C(=O)N1CCC[C@H]1c1ncc([nH]1)-c1ccc(cc1)-c1cc2cc(ccc2o1)-c1cnc([nH]1)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)OC)C(C)C
InChI Key InChIKey=QKFUCROVTLGTAV-UHFFFAOYSA-N
Data 16 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 16 hits for monomerid = 50147212
TargetNuclear receptor subfamily 1 group I member 2(Human)
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataEC50: 3.30E+3nMAssay Description:Activation of PXR (unknown origin)More data for this Ligand-Target Pair
Affinity DataEC50: 2.30nMAssay Description:Inhibition of HCV NS5A Y93H mutant in HCV genotype 1b assessed as reduction in viral replication by cell based replicon assayMore data for this Ligand-Target Pair
Affinity DataEC50: 6.40nMAssay Description:Inhibition of HCV NS5A L31V mutant in HCV genotype 1a assessed as reduction in viral replication by cell based replicon assayMore data for this Ligand-Target Pair
Affinity DataEC50: 8.80nMAssay Description:Inhibition of HCV NS5A Y93C mutant in HCV genotype 1a assessed as reduction in viral replication by cell based replicon assayMore data for this Ligand-Target Pair
Affinity DataEC50: 20nMAssay Description:Inhibition of HCV NS5A Y93H mutant in HCV genotype 1a assessed as reduction in viral replication by cell based replicon assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.5nMAssay Description:Inhibition of HCV NS5A L31V mutant in HCV genotype 1b assessed as reduction in viral replication by cell based replicon assayMore data for this Ligand-Target Pair
Affinity DataEC50: 8.5nMAssay Description:Inhibition of HCV NS5A Q30R mutant in HCV genotype 1a assessed as reduction in viral replication by cell based replicon assayMore data for this Ligand-Target Pair
Affinity DataEC50: 5.5nMAssay Description:Inhibition of HCV NS5A Q30H mutant in HCV genotype 1a assessed as reduction in viral replication by cell based replicon assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.00400nMAssay Description:Inhibition of HCV NS5A M28V mutant in HCV genotype 1a assessed as reduction in viral replication by cell based replicon assayMore data for this Ligand-Target Pair
Affinity DataEC50: 286nMAssay Description:Inhibition of HCV NS5A in HCV genotype 2b assessed as reduction in viral replication by cell based replicon assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.400nMAssay Description:Inhibition of HCV NS5A in HCV genotype 2a assessed as reduction in viral replication by cell based replicon assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.00100nMAssay Description:Inhibition of HCV NS5A in HCV genotype 1b assessed as reduction in viral replication by cell based replicon assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.300nMAssay Description:Inhibition of HCV NS5A in HCV genotype 4a assessed as reduction in viral replication by cell based replicon assayMore data for this Ligand-Target Pair
Affinity DataEC50: 4nMAssay Description:Inhibition of HCV NS5A in HCV genotype 3a assessed as reduction in viral replication by cell based replicon assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.0100nMAssay Description:Inhibition of HCV NS5A in HCV genotype 1a assessed as reduction in viral replication by cell based replicon assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.00200nMAssay Description:Measurement of inhibition by compounds was performed using the HCV replicon system. Several different replicons encoding different HCV genotypes or m...More data for this Ligand-Target Pair