BDBM50146910 (E)-N-[({2,4-Dichloro-3-[2-methyl-4-(pyridin-2-ylmethoxy)-quinolin-8-yloxymethyl]-phenyl}-methyl-carbamoyl)-methyl]-3-[6-(2-pyridin-4-yl-acetylamino)-pyridin-3-yl]-acrylamide::CHEMBL98349

SMILES CN(C(=O)CNC(=O)\C=C\c1ccc(NC(=O)Cc2ccncc2)nc1)c1ccc(Cl)c(COc2cccc3c(OCc4ccccn4)cc(C)nc23)c1Cl

InChI Key InChIKey=MCSLMHUPKUACLG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50146910   

TargetB2 bradykinin receptor(Human)
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50146910((E)-N-[({2,4-Dichloro-3-[2-methyl-4-(pyridin-2-ylm...)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of [3H]BK (1.0 nM) binding to the human bradykinin receptor B2, expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed