BDBM50146909 CHEMBL99978::{8-[2,6-Dichloro-3-(methyl-{2-[3-(4-methylcarbamoyl-phenyl)-acryloylamino]-acetyl}-amino)-benzyloxy]-2-methyl-quinolin-4-yloxy}-acetic acid

SMILES CNC(=O)c1ccc(\C=C\C(=O)NCC(=O)N(C)c2ccc(Cl)c(COc3cccc4c(OCC(O)=O)cc(C)nc34)c2Cl)cc1

InChI Key InChIKey=SXOGLZRMNGKCAB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50146909   

TargetB2 bradykinin receptor(Human)
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50146909({8-[2,6-Dichloro-3-(methyl-{2-[3-(4-methylcarbamoy...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of [3H]BK (1.0 nM) binding to the human bradykinin receptor B2, expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetB2 bradykinin receptor(Human)
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50146909({8-[2,6-Dichloro-3-(methyl-{2-[3-(4-methylcarbamoy...)
Affinity DataIC50: 50nMAssay Description:Concentration required to inhibit specific binding of [3H]-BK(0.06 nM) to the bradykinin receptor B2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed