BDBM50146900 (E)-3-(6-Acetylamino-pyridin-3-yl)-N-[({2,4-dichloro-3-[2-methoxy-1-(2-methoxy-ethyl)-1H-benzoimidazol-4-yloxymethyl]-phenyl}-methyl-carbamoyl)-methyl]-acrylamide::CHEMBL329758

SMILES COCCn1c(OC)nc2c(OCc3c(Cl)ccc(N(C)C(=O)CNC(=O)\C=C\c4ccc(NC(C)=O)nc4)c3Cl)cccc12

InChI Key InChIKey=FFBBRBMZBZYBQC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50146900   

TargetB2 bradykinin receptor(Human)
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50146900((E)-3-(6-Acetylamino-pyridin-3-yl)-N-[({2,4-dichlo...)
Affinity DataIC50: 3.5nMAssay Description:Inhibition of [3H]BK (1.0 nM) binding to the human bradykinin receptor B2, expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetB2 bradykinin receptor(Human)
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50146900((E)-3-(6-Acetylamino-pyridin-3-yl)-N-[({2,4-dichlo...)
Affinity DataIC50: 4.60nMAssay Description:Concentration required to inhibit specific binding of [3H]-BK(0.06 nM) to the bradykinin receptor B2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed