BDBM50146898 4-{(E)-2-[({[2,4-Dichloro-3-(4-dimethylcarbamoylmethoxy-2-methyl-quinolin-8-yloxymethyl)-phenyl]-methyl-carbamoyl}-methyl)-carbamoyl]-vinyl}-N-methyl-benzamide; hydrochloride::CHEMBL538020

SMILES CNC(=O)c1ccc(\C=C\C(=O)NCC(=O)N(C)c2ccc(Cl)c(COc3cccc4c(OCC(=O)N(C)C)cc(C)nc34)c2Cl)cc1

InChI Key InChIKey=KJFWCELSALPZRR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50146898   

TargetB2 bradykinin receptor(Human)
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50146898(4-{(E)-2-[({[2,4-Dichloro-3-(4-dimethylcarbamoylme...)
Affinity DataIC50: 3.70nMAssay Description:Inhibition of [3H]BK (1.0 nM) binding to the human bradykinin receptor B2, expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetB2 bradykinin receptor(Human)
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50146898(4-{(E)-2-[({[2,4-Dichloro-3-(4-dimethylcarbamoylme...)
Affinity DataIC50: 30nMAssay Description:Concentration required to inhibit specific binding of [3H]-BK(0.06 nM) to the bradykinin receptor B2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed