BDBM50146896 (E)-3-(6-Acetylamino-pyridin-3-yl)-N-({[3-(1-benzyl-2-methoxy-1H-benzoimidazol-4-yloxymethyl)-2,4-dichloro-phenyl]-methyl-carbamoyl}-methyl)-acrylamide::CHEMBL97393

SMILES COc1nc2c(OCc3c(Cl)ccc(N(C)C(=O)CNC(=O)\C=C\c4ccc(NC(C)=O)nc4)c3Cl)cccc2n1Cc1ccccc1

InChI Key InChIKey=UQZKWICEEMTXKM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50146896   

TargetB2 bradykinin receptor(Human)
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50146896((E)-3-(6-Acetylamino-pyridin-3-yl)-N-({[3-(1-benzy...)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of [3H]BK (1.0 nM) binding to the human bradykinin receptor B2, expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetB2 bradykinin receptor(Human)
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50146896((E)-3-(6-Acetylamino-pyridin-3-yl)-N-({[3-(1-benzy...)
Affinity DataIC50: 26nMAssay Description:Concentration required to inhibit specific binding of [3H]-BK(0.06 nM) to the bradykinin receptor B2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed