BDBM50146890 CHEMBL540300::{8-[2,6-Dichloro-3-(methyl-{2-[(E)-3-(4-methylcarbamoyl-phenyl)-acryloylamino]-acetyl}-amino)-benzyloxy]-2-methyl-quinolin-4-yloxy}-acetic acid ethyl ester; hydrochloride

SMILES CCOC(=O)COc1cc(C)nc2c(OCc3c(Cl)ccc(N(C)C(=O)CNC(=O)\C=C\c4ccc(cc4)C(=O)NC)c3Cl)cccc12

InChI Key InChIKey=GTXMALXTVPPBMA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50146890   

TargetB2 bradykinin receptor(Human)
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50146890({8-[2,6-Dichloro-3-(methyl-{2-[(E)-3-(4-methylcarb...)
Affinity DataIC50: 20nMAssay Description:Concentration required to inhibit specific binding of [3H]-BK(0.06 nM) to the bradykinin receptor B2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetB2 bradykinin receptor(Human)
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50146890({8-[2,6-Dichloro-3-(methyl-{2-[(E)-3-(4-methylcarb...)
Affinity DataIC50: 2.60nMAssay Description:Inhibition of [3H]BK (1.0 nM) binding to the human bradykinin receptor B2, expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed