BDBM50146597 CHEMBL3763941

SMILES O=C1CCCC(=O)N1

InChI Key InChIKey=KNCYXPMJDCCGSJ-UHFFFAOYSA-N

Data  4 KI  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50146597   

TargetCereblon isoform 4(Magnetospirillum gryphiswaldense)
Max Planck Institute For Developmental Biology

Curated by ChEMBL
LigandPNGBDBM50146597(CHEMBL3763941)
Affinity DataIC50: 4.89E+4nMAssay Description:Inhibition of MANT-uracil binding to wild type Magnetospirillum gryphiswaldense cereblon isoform 4 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/17/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProtein cereblon(Human)
Max Planck Institute For Developmental Biology

Curated by ChEMBL
LigandPNGBDBM50146597(CHEMBL3763941)
Affinity DataIC50: 1.36E+5nMAssay Description:Inhibition of MANT-uracil binding to human CRBN (delta 1 to 315) by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/17/2017
Entry Details Article
PubMed
TargetCereblon isoform 4(Magnetospirillum gryphiswaldense)
Max Planck Institute For Developmental Biology

Curated by ChEMBL
LigandPNGBDBM50146597(CHEMBL3763941)
Affinity DataKi:  2.78E+4nMAssay Description:Inhibition of MANT-uracil binding to wild type Magnetospirillum gryphiswaldense cereblon isoform 4 by Cheng-Prusoff equation analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/17/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCereblon isoform 4(Magnetospirillum gryphiswaldense)
Max Planck Institute For Developmental Biology

Curated by ChEMBL
LigandPNGBDBM50146597(CHEMBL3763941)
Affinity DataKi:  2.80E+4nMAssay Description:Inhibition of MANT-uracil binding to wild-type Magnetospirillum gryphiswaldense CRBN isoform 4 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProtein cereblon(Human)
Max Planck Institute For Developmental Biology

Curated by ChEMBL
LigandPNGBDBM50146597(CHEMBL3763941)
Affinity DataKi:  2.80E+4nMAssay Description:Binding affinity to CRBN (unknown origin) assessed as inhibition constant by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetProtein cereblon(Human)
Max Planck Institute For Developmental Biology

Curated by ChEMBL
LigandPNGBDBM50146597(CHEMBL3763941)
Affinity DataKi:  1.03E+5nMAssay Description:Inhibition of MANT-uracil binding to human CRBN (delta 1 to 315) by Cheng-Prusoff equation analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/17/2017
Entry Details Article
PubMed