BDBM50146579 Benzyl-O-Hydroxylamine::CHEMBL443652::O-Benzylhydroxylamine

SMILES NOCc1ccccc1

InChI Key InChIKey=XYEOALKITRFCJJ-UHFFFAOYSA-N

Data  1 KI  3 IC50

PDB links: 2 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50146579   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Bryn Mawr College

Curated by ChEMBL
LigandPNGBDBM50146579(Benzyl-O-Hydroxylamine | O-Benzylhydroxylamine | C...)
Affinity DataIC50: 810nMAssay Description:Inhibition of recombinant human IDO1 assessed as reduction in kynurenine production using L-tryptophan as substrate after 60 mins by microplate reade...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/16/2017
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Bryn Mawr College

Curated by ChEMBL
LigandPNGBDBM50146579(Benzyl-O-Hydroxylamine | O-Benzylhydroxylamine | C...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human IDO using L-tryptophan as substrate preincubated for 5 mins followed by substrate addition measured after 15 mins by spectrophoto...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetAlanine--glyoxylate aminotransferase(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50146579(Benzyl-O-Hydroxylamine | O-Benzylhydroxylamine | C...)
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of recombinant wild type His-tagged AGT (unknown origin) expressed in Escherichia coli BL21 using L-alanine and glyoxylate as a substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetAlanine--glyoxylate aminotransferase(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50146579(Benzyl-O-Hydroxylamine | O-Benzylhydroxylamine | C...)
Affinity DataKi:  600nMAssay Description:Inhibition of recombinant wild type His-tagged AGT (unknown origin) expressed in Escherichia coli BL21 assessed as inhibition constant using L-alanin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed